As video games are traditionally a medium for males, and most males are heterosexual, most of the romance happens between a male character and a female NPC of the player's choice. This more often than not happens in more open-ended games, such as RPGs and Wide Open Sandbox games like Grand Theft Auto, rather than games that follow a tight, ' every note must be hit' plot, where any romance happens at the behest of the story.
Oftentimes in video games, the option exists for the main character to pursue a romantic relationship with some other character. Jimmy Hopkins, making the Gay Option work for him.